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  Protein-based nanobiomaterials: Antibodies, vaccine and enzymes
 

 

Technical approach

Research leader

Research assistants

Post-doc researchers

Students

Selected publications

 

Protein- based nanomaterials : Antibodies, vaccine and enzymes

The mission of the laboratory is to bridge the gap between nanotechnology and molecular medicine researches, translating novel discoveries into cutting-edge tests and accelerating the translation of nanomedicine discoveries into cancer therapy. The main research programs of this laboratory are on nanobiosensing focused on cancer diagnosis areas. Biosensor technology is probably one of the fastest growing areas to early detection of cancers. As aptamers show high target affinity and high target specificity, they can be used as therapeutic agents, in affinity columns and as recognition elements in sensors detecting a wide range of targets. Then, our group focused to designing of aptamers and apobody-based optical and electrochemical biosensors to cancer detection. The SELEX process that is a technique for screening a very large library of oligonucleotides with random sequences by iterative cycles of selection and amplification has been used in our laboratory.


Technical approach

PCR and RT-PCR

DNA cloning

Genetic manipulation of bacteria, microalgae & yeast

Aptamer designingApo-body designing

Phag display Technology

Cancer biomarker discovering

 

 

 

Research Leader


Dr. Mohammad Reza Tohidkia, (M.Sc, PhD)
Dr. Mohammad Mostafa Pourseif, (M.Sc, PhD)
Dr.Azam Safary, (M.Sc, PhD)
Dr. Ali mesghary shadi, (M.Sc, PhD)

Dr.Jaber  dehghani,(M.Sc,PhD)
Prof. Yadollah Omidi, (PharmD, Ph.D)

 

Research Assistants

Rahimeh Mousavi

 

 

Post-doc Researchers

 

 
 
Jaber Dehghani received his B.S. degree in plant biology in 2008 from Zabol University and his M.S degree in plant developmental cell biology in 2012 from Tabriz University (the one of best university in Iran). Immediately, he started Ph.D. studying in plant cellular and molecular biology in University of Tabriz, as a top student in the entrance exam of universities. Presently, he focused on molecular identification of micro-algae and production of recombinant proteins.
 
 

Students

PhD Students

 
Hadi Maleki Kakelar obtained his BSc in Biology in 2007 and MSc in Microbiology in 2010 from Islamic Azad University of Zanjan. His major is cellular/molecular biology. He started his Ph.D. in nanobiomedicine in Tabriz University of Medical Sciences (TUOMS), Tabriz, Iran in 2014. Hadi is greatly dedicated to his work, and possesses unparalleled ability in research activities which make him a significant researcher. He meets deadlines and conducts pure research. His creative mind and curiosity paves his way for future achievements and successes.
Somayeh Vandghanooni received M.Sc (2007) of genetics and B.Sc of biology (2005) from the department of biology-genetic of Tabriz University. Her M.Sc project was about studying survivin gene expression and its splice variants as diagnostic biomarkers for malignant papillary thyroid tumors.  She was a member of exceptional talent organization during her education in both courses at university of Tabriz. She started her PhD in nanobiotechnology (2014) at Research Center for Pharmaceutical Nanotechnology (RCPN), Tabriz University of Medical Sciences, Tabriz, Iran. Her PhD thesis is about the engineering of targeted drug delivery nanomachinery system for ovarian cancer chemo/gene therapy which is in progress under the supervision of Prof. Y. Omidi and Prof. J. Barar and advising of Dr. Eskandani.  
 

 









 

 

 

 












 

 



Selected Publication based on scopus

Last two years publications (2017-2018)

 

 

1.         Fahimi F, Sarhaddi S, Fouladi M, Samadi N, Sadeghi J, Golchin A, et al. Phage display-derived antibody fragments against conserved regions of VacA toxin of Helicobacter pylori. Applied Microbiology and Biotechnology. 2018;102(16):6899-913.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047945292&doi=10.1007%2fs00253-018-9068-4&partnerID=40&md5=9865ce9575ce57fa5aa503cc230c58cc

2.         Fahimi F, Tohidkia MR, Fouladi M, Aqabeigi R, Samadi N, Omidi Y. Pleiotropic cytotoxicity of VacA toxin in host cells and its impact on immunotherapy. BioImpacts. 2017;7(1):59-71.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019068034&doi=10.15171%2fbi.2017.08&partnerID=40&md5=27df4ff00dca992299baaf7900741991

3.         Gharaati-Far N, Tohidkia MR, Dehnad A, Omidi Y. Efficiency and cytotoxicity analysis of cationic lipids-mediated gene transfection into AGS gastric cancer cells. Artificial Cells, Nanomedicine and Biotechnology. 2018;46(5):1001-8.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85025432439&doi=10.1080%2f21691401.2017.1355311&partnerID=40&md5=a3cdfc55a52ef3259f8757b28e68e386

4.         Khajeh S, Tohidkia MR, Aghanejad A, Mehdipour T, Fathi F, Omidi Y. Phage display selection of fully human antibody fragments to inhibit growth-promoting effects of glycine-extended gastrin 17 on human colorectal cancer cells. Artificial Cells, Nanomedicine and Biotechnology. 2018:1-9.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048189454&doi=10.1080%2f21691401.2018.1478846&partnerID=40&md5=c380e2f8405070fb03565a8153786c0c

5.         Tohidkia MR, Sepehri M, Khajeh S, Barar J, Omidi Y. Improved Soluble ScFv ELISA Screening Approach for Antibody Discovery Using Phage Display Technology. SLAS Discovery. 2017;22(8):1026-34.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019103807&doi=10.1177%2f2472555217701059&partnerID=40&md5=af31b18c9d2b27f21c12bcabf6ab2098

6.         Asgharzadeh MR, Barar J, Pourseif MM, Eskandani M, Niya MJ, Mashayekhi MR, et al. Molecular machineries of pH dysregulation in tumor microenvironment: Potential targets for cancer therapy. BioImpacts. 2017;7(2):115-33.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027460324&doi=10.15171%2fbi.2017.15&partnerID=40&md5=0829735dfa89423eb093a6fc07cea2ec

7.         Dehghani J, Adibkia K, Movafeghi A, Barzegari A, Pourseif MM, Maleki Kakelar H, et al. Stable transformation of Spirulina (Arthrospira) platensis: a promising microalga for production of edible vaccines. Applied Microbiology and Biotechnology. 2018;102(21):9267-78.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052698199&doi=10.1007%2fs00253-018-9296-7&partnerID=40&md5=a973db2f6e09da62affb59742cc327ab

8.         Pourseif MM, Moghaddam G, Daghighkia H, Nematollahi A, Omidi Y. A novel B- and helper T-cell epitopes-based prophylactic vaccine against Echinococcus granulosus. BioImpacts. 2018;8(1):39-52.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044310762&doi=10.15171%2fbi.2018.06&partnerID=40&md5=ea0ff8f030d068035ab94721a89bd101

9.         Pourseif MM, Moghaddam G, Naghili B, Saeedi N, Parvizpour S, Nematollahi A, et al. A novel in silico minigene vaccine based on CD4+ T-helper and B-cell epitopes of EG95 isolates for vaccination against cystic echinococcosis. Computational Biology and Chemistry. 2018;72:150-63.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85035245058&doi=10.1016%2fj.compbiolchem.2017.11.008&partnerID=40&md5=b0f720db7f8ae2e7b24b3291b687b69c

10.       Pourseif MM, Moghaddam G, Saeedi N, Barzegari A, Dehghani J, Omidi Y. Current status and future prospective of vaccine development against Echinococcus granulosus. Biologicals : journal of the International Association of Biological Standardization. 2018;51:1-11.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032934489&doi=10.1016%2fj.biologicals.2017.10.003&partnerID=40&md5=6e58b3fd4e237e6da7d3f19237f99091

11.       Safary A, Khiavi MA, Mousavi R, Barar J, Rafi MA. Enzyme replacement therapies: What is the best option? BioImpacts. 2018;8(3):153-7.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050655722&doi=10.15171%2fbi.2018.17&partnerID=40&md5=2be2cddf621c4edf67048c83097c1868

12.       Abdollahi-Aghdam A, Majidi MR, Omidi Y. Microfluidic paper-based analytical devices (µPADs) for fast and ultrasensitive sensing of biomarkers and monitoring of diseases. BioImpacts. 2018;8(4):237-40.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056101467&doi=10.15171%2fbi.2018.26&partnerID=40&md5=c674c653dbde0f25069a0698908ef29a

13.       Aghanejad A, Babamiri H, Adibkia K, Barar J, Omidi Y. Mucin-1 aptamer-armed superparamagnetic iron oxide nanoparticles for targeted delivery of doxorubicin to breast cancer cells. BioImpacts. 2018;8(2):117-27.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048082430&doi=10.15171%2fbi.2018.14&partnerID=40&md5=5f8a4a5ed2e47f4ada46ef978cfdd4a9

14.       Akbari Nakhjavani S, Khalilzadeh B, Samadi Pakchin P, Saber R, Ghahremani MH, Omidi Y. A highly sensitive and reliable detection of CA15-3 in patient plasma with electrochemical biosensor labeled with magnetic beads. Biosensors and Bioelectronics. 2018;122:8-15.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053379901&doi=10.1016%2fj.bios.2018.08.047&partnerID=40&md5=c925ecd2ebd8ae18c0a362c531e6c248

15.       Arteshi Y, Aghanejad A, Davaran S, Omidi Y. Biocompatible and electroconductive polyaniline-based biomaterials for electrical stimulation. European Polymer Journal. 2018;108:150-70.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052655195&doi=10.1016%2fj.eurpolymj.2018.08.036&partnerID=40&md5=2ee775b9cc2c2beb4aacd3f11134e449

16.       Asghari S, Movafeghi A, Lisar SYS, Barar J, Omidi Y. Effects of phenanthrene on growth parameters and antioxidant systems in the green microalga chlorella vulgaris. Biointerface Research in Applied Chemistry. 2018;8(4):3405-11.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052365437&partnerID=40&md5=fdc89489e2d84bf2c4f97641305ed271

17.       Asoudeh-Fard A, Barzegari A, Dehnad A, Bastani S, Golchin A, Omidi Y. Lactobacillus plantarum induces apoptosis in oral cancer KB cells through upregulation of PTEN and downregulation of MAPK signaling pathways. BioImpacts. 2017;7(3):193-8.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032022290&doi=10.15171%2fbi.2017.22&partnerID=40&md5=ac2f9710e0d21efbaf6eadd4a80bb0ae

18.       Bakhtiary Z, Barar J, Aghanejad A, Saei AA, Nemati E, Ezzati Nazhad Dolatabadi J, et al. Microparticles containing erlotinib-loaded solid lipid nanoparticles for treatment of non-small cell lung cancer. Drug Development and Industrial Pharmacy. 2017;43(8):1244-53.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017243891&doi=10.1080%2f03639045.2017.1310223&partnerID=40&md5=a3a4450cf9f6ed9163e9604b2ef7c165

19.       Borran AA, Aghanejad A, Farajollahi A, Barar J, Omidi Y. Gold nanoparticles for radiosensitizing and imaging of cancer cells. Radiation Physics and Chemistry. 2018;152:137-44.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052432811&doi=10.1016%2fj.radphyschem.2018.08.010&partnerID=40&md5=3541b56118a7bcedc235d59528aac342

20.       Daryanoosh M, Goudarzi G, Rashidi R, Keishams F, Hopke PK, Mohammadi MJ, et al. Risk of morbidity attributed to ambient PM<inf>10</inf>in the western cities of Iran. Toxin Reviews. 2017:1-6.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029411025&doi=10.1080%2f15569543.2017.1370602&partnerID=40&md5=af4f94f3f2ce72fc53ab7f47143e422a

21.       Eskandani M, Vandghanooni S, Barar J, Nazemiyeh H, Omidi Y. Cell physiology regulation by hypoxia inducible factor-1: Targeting oxygen-related nanomachineries of hypoxic cells. International Journal of Biological Macromolecules. 2017;99:46-62.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013761924&doi=10.1016%2fj.ijbiomac.2016.10.113&partnerID=40&md5=4d609bc880884abb22a518041b6a9202

22.       Fathi M, Majidi S, Zangabad PS, Barar J, Erfan-Niya H, Omidi Y. Chitosan-based multifunctional nanomedicines and theranostics for targeted therapy of cancer. Medicinal Research Reviews. 2018;38(6):2110-36.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047824876&doi=10.1002%2fmed.21506&partnerID=40&md5=2566096631e3941d12b78325dd476100

23.       Fathi M, Sahandi Zangabad P, Barar J, Aghanejad A, Erfan-Niya H, Omidi Y. Thermo-sensitive chitosan copolymer-gold hybrid nanoparticles as a nanocarrier for delivery of erlotinib. International Journal of Biological Macromolecules. 2018;106:266-76.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027684914&doi=10.1016%2fj.ijbiomac.2017.08.020&partnerID=40&md5=e863c26424866b7f5d93d67e01215d6f

24.       Fathi M, Zangabad PS, Aghanejad A, Barar J, Erfan-Niya H, Omidi Y. Folate-conjugated thermosensitive O-maleoyl modified chitosan micellar nanoparticles for targeted delivery of erlotinib. Carbohydrate Polymers. 2017;172:130-41.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019350573&doi=10.1016%2fj.carbpol.2017.05.007&partnerID=40&md5=14fbcf7b855cc5fa0b6748f93b7f9e81

25.       Fathi M, Zangabad PS, Majidi S, Barar J, Erfan-Niya H, Omidi Y. Stimuli-responsive chitosan-based nanocarriers for cancer therapy. BioImpacts. 2017;7(4):269-77.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041008382&doi=10.15171%2fbi.2017.32&partnerID=40&md5=a3481207a7941102508acbaa32214868

26.       Ferdousi R, Safdari R, Omidi Y. Computational prediction of drug-drug interactions based on drugs functional similarities. Journal of Biomedical Informatics. 2017;70:54-64.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019088981&doi=10.1016%2fj.jbi.2017.04.021&partnerID=40&md5=098782278979906f40d9f9cf2d2f249a

27.       Goudarzi G, Daryanoosh SM, Godini H, Hopke PK, Sicard P, De Marco A, et al. Health risk assessment of exposure to the Middle-Eastern Dust storms in the Iranian megacity of Kermanshah. Public Health. 2017;148:109-16.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018443434&doi=10.1016%2fj.puhe.2017.03.009&partnerID=40&md5=118cb4edffb7174767f7edb4c8ed3a79

28.       Jafarizad A, Aghanejad A, Sevim M, Metin Ö, Barar J, Omidi Y, et al. Gold Nanoparticles and Reduced Graphene Oxide-Gold Nanoparticle Composite Materials as Covalent Drug Delivery Systems for Breast Cancer Treatment. ChemistrySelect. 2017;2(23):6663-72.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041836352&doi=10.1002%2fslct.201701178&partnerID=40&md5=6b0fbea4224f638561de41f6c3d258db

29.       Karami P, Majidi MR, Johari-Ahar M, Barar J, Omidi Y. Development of screen-printed tryptophan-kynurenine immunosensor for in vitro assay of kynurenine-mediated immunosuppression effect of cancer cells on activated T-cells. Biosensors and Bioelectronics. 2017;92:287-93.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006493516&doi=10.1016%2fj.bios.2016.11.010&partnerID=40&md5=edf3bfa31406b3199bdbafafe9ee161f

30.       Maleki Kakelar H, Barzegari A, Dehghani J, Hanifian S, Saeedi N, Barar J, et al. Pathogenicity of Helicobacter pylori in cancer development and impacts of vaccination. Gastric Cancer. 2018.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052663819&doi=10.1007%2fs10120-018-0867-1&partnerID=40&md5=001fe9f33fed1270945f9b525363283a

31.       Mesgari-Shadi A, Sarrafzadeh MH, Barar J, Omidi Y. Cost-effective batch production process of scFv antibody in Escherichia coli. Human Antibodies. 2017;26(3):149-57.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047346843&doi=10.3233%2fHAB-180333&partnerID=40&md5=915f30b6a94c90f2b0f4346a9193cd20

32.       Mesgari-Shadi A, Sarrafzadeh MH, Divband B, Barar J, Omidi Y. Batch adsorption/desorption for purification of scFv antibodies using nanozeolite microspheres. Microporous and Mesoporous Materials. 2018;264:167-75.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041469002&doi=10.1016%2fj.micromeso.2018.01.028&partnerID=40&md5=28865cc8862f3d164597a2826580f3f9

33.       Mohammadi MJ, Yari AR, Saghazadeh M, Sobhanardakani S, Geravandi S, Afkar A, et al. A health risk assessment of heavy metals in people consuming Sohan in Qom, Iran. Toxin Reviews. 2017:1-9.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028539918&doi=10.1080%2f15569543.2017.1362655&partnerID=40&md5=b6fbf045c1c7b21deb47e9a81c6d4566

34.       Momtazan M, Geravandi S, Rastegarimehr B, Valipour A, Ranjbarzadeh A, Yari AR, et al. An investigation of particulate matter and relevant cardiovascular risks in Abadan and Khorramshahr in 2014–2016. Toxin Reviews. 2018:1-8.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045837160&doi=10.1080%2f15569543.2018.1463266&partnerID=40&md5=f22d5ddfffe0b78faf65bd8070f5854e

35.       Nakhlband A, Eskandani M, Omidi Y, Saeedi N, Ghaffari S, Barar J, et al. Combating atherosclerosis with targeted nanomedicines: Recent advances and future prospective. BioImpacts. 2018;8(1):59-75.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044298919&doi=10.15171%2fbi.2018.08&partnerID=40&md5=c44d352eea40fe79a5840b756e3d8c49

36.       Nakhlband A, Eskandani M, Saeedi N, Ghafari S, Omidi Y, Barar J, et al. Marrubiin-loaded solid lipid nanoparticles’ impact on TNF-α treated umbilical vein endothelial cells: A study for cardioprotective effect. Colloids and Surfaces B: Biointerfaces. 2018;164:299-307.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041484199&doi=10.1016%2fj.colsurfb.2018.01.046&partnerID=40&md5=75a93e53a55737af8ff5751d49c96e8d

37.       Neisi A, Albooghobeish M, Geravandi S, Adeli Behrooz HR, Mahboubi M, Omidi Khaniabad Y, et al. Investigation of health risk assessment sevoflurane on indoor air quality in the operation room in Ahvaz city, Iran. Toxin Reviews. 2018:1-9.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042079259&doi=10.1080%2f15569543.2018.1434796&partnerID=40&md5=7743c13a195a1e81870c69af75f654d0

38.       Neisi A, Idani E, Vosoughi M, Hazrati S, Babaei AA, Takdastan A, et al. Answers to the comments on “Air pollution, biological marker and lung function in children”. Environmental Science and Pollution Research. 2018;25(27):27669-71.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051662886&doi=10.1007%2fs11356-018-2905-2&partnerID=40&md5=67ebae1b334f8ee7ae0b9613c4dbb3c5

39.       Nemati E, Azami A, Mokhtarzadeh A, Rahbar Saadat Y, Omidi Y, Ezzati Nazhad Dolatabadi J. Formulation and characterization of ethambutol loaded nanostructured lipid carrier. Latin American Journal of Pharmacy. 2017;36(2):247-52.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009188311&partnerID=40&md5=0dd9090004b9a8389b901191bc5aa7b0

40.       Omidi Khaniabadi Y, Sicard P, Omidi Khaniabadi A, Mohammadinejad S, Keishams F, Takdastan A, et al. Air quality modeling for health risk assessment of ambient PM<inf>10</inf>, PM<inf>2.5</inf> and SO<inf>2</inf> in Iran. Human and Ecological Risk Assessment. 2018.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056076901&doi=10.1080%2f10807039.2018.1487277&partnerID=40&md5=4ad5db9621bada963912faeefebe885c

41.       Pakchin PS, Nakhjavani SA, Saber R, Ghanbari H, Omidi Y. Recent advances in simultaneous electrochemical multi-analyte sensing platforms. TrAC - Trends in Analytical Chemistry. 2017;92:32-41.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019062608&doi=10.1016%2fj.trac.2017.04.010&partnerID=40&md5=86f1d82fb0a639bf442abe990251d8d4

42.       Panahpour H, Farhoudi M, Omidi Y, Mahmoudi J. An in vivo assessment of blood-brain barrier disruption in a rat model of ischemic stroke. Journal of Visualized Experiments. 2018;2018(133).  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044652743&doi=10.3791%2f57156&partnerID=40&md5=3d54e84e447224149ceec28d52000563

43.       Parvizpour S, Razmara J, Omidi Y. Breast cancer vaccination comes to age: Impacts of bioinformatics. BioImpacts. 2018;8(3):223-35.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050689925&doi=10.15171%2fbi.2018.25&partnerID=40&md5=35bbff349a89fb1923d5cd2987fea1b2

44.       Rahmanian N, Eskandani M, Barar J, Omidi Y. Recent trends in targeted therapy of cancer using graphene oxide-modified multifunctional nanomedicines. Journal of Drug Targeting. 2017;25(3):202-15.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013790692&doi=10.1080%2f1061186X.2016.1238475&partnerID=40&md5=bd598c4cfefb872b3e2a2475014d55e9

45.       Ranjbar-Navazi Z, Eskandani M, Johari-Ahar M, Nemati A, Akbari H, Davaran S, et al. Doxorubicin-conjugated D-glucosamine- and folate- bi-functionalised InP/ZnS quantum dots for cancer cells imaging and therapy. Journal of Drug Targeting. 2018;26(3):267-77.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028533760&doi=10.1080%2f1061186X.2017.1365876&partnerID=40&md5=ecb973a8ad3ac8a67a759bfe5c6554a7

46.       Rodriguez-Ruiz V, Salatti-Dorado JÁ, Barzegari A, Nicolas-Boluda A, Houaoui A, Caballo C, et al. Astaxanthin-loaded nanostructured lipid carriers for preservation of antioxidant activity. Molecules. 2018;23(10).  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054802470&doi=10.3390%2fmolecules23102601&partnerID=40&md5=4c189dcfc787a799bb20b92924979f3d

47.       Salmanzadeh R, Eskandani M, Mokhtarzadeh A, Vandghanooni S, Ilghami R, Maleki H, et al. Propyl gallate (PG) and tert-butylhydroquinone (TBHQ) may alter the potential anti-cancer behavior of probiotics. Food Bioscience. 2018;24:37-45.  https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047079935&doi=10.1016%2fj.fbio.2018.05.005&partnerID=40&md5=86ec63b293c96c30b9a73dbb9b725882

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